Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902, Magnolia Drive, FOB1, Tampa, FL, 33612, USA. alberto.chiappori@moffitt.org. Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, 12902, Magnolia Drive, FOB1, Tampa, FL, 33612, USA. Department of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, 33612, USA. MD Anderson Cancer Center, Houston, TX, 77030, USA. Karmanos Cancer Institute, Detroit, MI, 48201, USA. Wistar Institute, Philadelphia, PA, 19104, USA.